[Effect of promoting biliation mixture on E. coli lipopolysaccharide under electron microscopy].

With electron microscopy this article observed the effect of promoting biliation mixture (PBM) and polymyxin B on E. coli lipopolysaccharide (LPS). The result showed that PBM could breakdown the typical structure of E. coli LPS with only short sections or partially disaggregate it. The morphology changes were similar to the effect of polymyxin B. It would appear that the loss of endotoxicity caused by PBM may be due to the loss of structural integrity of the E. coli LPS. The result may also give some evidence for the clinical effects of PBM theoretically.