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Percutaneous radiofrequency ablation for the treatment of hepatocellular carcinoma in the caudate lobe.
- Source :
-
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology [Eur J Surg Oncol] 2008 Feb; Vol. 34 (2), pp. 166-72. Date of Electronic Publication: 2007 Sep 11. - Publication Year :
- 2008
-
Abstract
- Aims: This study aimed to evaluate the efficacy and safety of percutaneous radiofrequency ablation (PRFA) for hepatocellular carcinoma (HCC) in the caudate lobe.<br />Patients and Methods: Between January 2001 and December 2006, 17 patients (twelve males and five females) who were between 33 and 68years old (mean 54.3), with caudate lobe HCC [2.0-6.5cm in diameter (mean 3.1)] were treated with either PRFA alone (n=14), or PRFA with percutaneous ethanol injection (n=3) under ultrasound guidance. The right or the anterior approach was used in 12 and 5 patients, respectively.<br />Results: All procedures were performed successfully. There was no mortality and major morbidity due to PRFA. Fourteen tumors (82%) were completely ablated after one to two sessions of treatment. During follow-up (range 3-60, mean 29.1months), two (14%) developed local recurrence. Intrahepatic metastases developed in 9 of 17 patients (53%). No distant metastasis was found. Four patients died (24%), 3 from tumor progression and 1 from hepatic failure. The 1-, 2-, and 4-year overall survivals were 88%, 80%, and 72%, respectively, and the progress free survivals were 47%, 20%, and 10%, respectively.<br />Conclusions: PRFA is efficacious and safe for patients with HCC in the caudate lobe.
- Subjects :
- Adult
Aged
Carcinoma, Hepatocellular mortality
Cohort Studies
Female
Follow-Up Studies
Hepatectomy methods
Humans
Kaplan-Meier Estimate
Length of Stay
Liver Neoplasms mortality
Male
Middle Aged
Minimally Invasive Surgical Procedures
Neoplasm Recurrence, Local mortality
Neoplasm Staging
Pain, Postoperative physiopathology
Probability
Retrospective Studies
Risk Assessment
Survival Analysis
Treatment Outcome
Carcinoma, Hepatocellular pathology
Carcinoma, Hepatocellular surgery
Catheter Ablation methods
Liver Neoplasms pathology
Liver Neoplasms surgery
Neoplasm Recurrence, Local pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2157
- Volume :
- 34
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 17851020
- Full Text :
- https://doi.org/10.1016/j.ejso.2007.08.004