Back to Search
Start Over
Twin fetuses with abnormalities that overlap with three midline malformation complexes.
- Source :
-
American journal of medical genetics [Am J Med Genet] 1991 Nov 01; Vol. 41 (2), pp. 230-5. - Publication Year :
- 1991
-
Abstract
- Twin fetuses aborted at an estimated gestational age of 145 days were concordant for oral, facial, skeletal, and central nervous system malformations. The twins were discordant for other anomalies including cardiac defects, polydactyly, and malrotated short bowel. The combination of malformations observed overlaps with that of the oral-facial-digital syndrome, hydrolethalus syndrome, and Pallister-Hall syndrome. The problem of phenotypic overlap between these syndromes is discussed.
- Subjects :
- Abnormalities, Multiple diagnosis
Abnormalities, Multiple pathology
Brain Neoplasms embryology
Cleft Palate
Diagnosis, Differential
Female
Fetal Diseases pathology
Hamartoma embryology
Heart Defects, Congenital embryology
Humans
Hypothalamus
Limb Deformities, Congenital
Occipital Bone abnormalities
Orofaciodigital Syndromes diagnosis
Phenotype
Prenatal Diagnosis
Syndrome
Twins, Monozygotic
Abnormalities, Multiple classification
Diseases in Twins
Fetus abnormalities
Orofaciodigital Syndromes pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0148-7299
- Volume :
- 41
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- American journal of medical genetics
- Publication Type :
- Academic Journal
- Accession number :
- 1785640
- Full Text :
- https://doi.org/10.1002/ajmg.1320410220