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[Clinical repercussion of the 6th edition TNM staging system classification on differentiated thyroid carcinoma].
- Source :
-
Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2007 Jul; Vol. 51 (5), pp. 825-31. - Publication Year :
- 2007
-
Abstract
- The TNM classification of UICC is used for predicting the outcome of thyroid cancer. The 6th edition changed the description of primary tumor (T), regional lymph node (N) and the staging group. The aim of this study was to compare the ability of the 5th and the 6th editions to predict outcome. The two classifications were applied in a retrospective analysis of 90 patients from HUCFF. Sixty-nine patients had papillary carcinoma, 14 follicular, 4 Hürthle cell, and 3 mixed. Patients were followed for a mean period of 58.3 months. At the end of follow-up, 49 patients were disease-free, 23 persisted with disease, 4 had cervical recurrence, 11 had metastases and 3 died. According to the 6th edition, 19 patients were classified as T1, compared to 7 based on the 5th edition; 19 patients were T2 compared to 30; 14 were T3 compared to 10; 22 were T4 compared to 27, and 16 patients were Tx. Both editions showed comparable remissions for stages I, II, and III. For the stage IV there was a significant change in remission, however there was no difference comparing IV and IV C.
- Subjects :
- Adenocarcinoma, Follicular mortality
Adenocarcinoma, Follicular surgery
Adolescent
Adult
Aged
Carcinoma, Papillary mortality
Carcinoma, Papillary surgery
Epidemiologic Methods
Female
Humans
Lymph Nodes pathology
Lymphatic Metastasis
Male
Middle Aged
Neck Dissection
Neoplasm Invasiveness
Neoplasm Recurrence, Local
Neoplasm Staging
Thyroid Neoplasms mortality
Thyroid Neoplasms surgery
Thyroidectomy methods
Adenocarcinoma, Follicular pathology
Carcinoma, Papillary pathology
Thyroid Neoplasms pathology
Subjects
Details
- Language :
- Portuguese
- ISSN :
- 0004-2730
- Volume :
- 51
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Arquivos brasileiros de endocrinologia e metabologia
- Publication Type :
- Academic Journal
- Accession number :
- 17891247
- Full Text :
- https://doi.org/10.1590/s0004-27302007000500021