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T helper 17 cells get the NOD.

Authors :
Stetson DB
Medzhitov R
Source :
Immunity [Immunity] 2007 Oct; Vol. 27 (4), pp. 546-8.
Publication Year :
2007

Abstract

Interleukin-17 (IL-17)-producing helper T cells play a role in pathogen defense and autoimmunity. In this issue of Immunity, van Beelen et al. (2007) reveal a pathway that elicits potent IL-17 production from memory T cells through activation of the intracellular receptor NOD2.

Subjects

Subjects :
Animals
Humans
Immunologic Memory
Interleukin-17 immunology
T-Lymphocyte Subsets metabolism
T-Lymphocytes, Helper-Inducer metabolism
Interleukin-17 biosynthesis
Nod2 Signaling Adaptor Protein metabolism
T-Lymphocyte Subsets immunology
T-Lymphocytes, Helper-Inducer immunology

Details

Language :
English
ISSN :
1074-7613
Volume :
27
Issue :
4
Database :
MEDLINE
Journal :
Immunity
Publication Type :
Academic Journal
Accession number :
17967409
Full Text :
https://doi.org/10.1016/j.immuni.2007.10.005
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