PfamAlyzer: domain-centric homology search.

Authors :: Hollich V
Sonnhammer EL
Source :: Bioinformatics (Oxford, England) [Bioinformatics] 2007 Dec 15; Vol. 23 (24), pp. 3382-3. Date of Electronic Publication: 2007 Oct 31.
Publication Year :: 2007
Abstract: Unlabelled: PfamAlyzer is a Java applet that enables exploration of Pfam domain architectures using a user-friendly graphical interface. It can search the UniProt protein database for a domain pattern. Domain patterns similar to the query are presented graphically by PfamAlyzer either in a ranked list or pinned to the tree of life. Such domain-centric homology search can assist identification of distant homologs with shared domain architecture.<br />Availability: PfamAlyzer has been integrated with the Pfam database and can be accessed at http://pfam.cgb.ki.se/pfamalyzer.