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Large-cell neuroendocrine carcinoma of the skin, with lymphoid stroma.
- Source :
-
The American Journal of dermatopathology [Am J Dermatopathol] 2007 Dec; Vol. 29 (6), pp. 578-80. - Publication Year :
- 2007
-
Abstract
- We report two cases of a large-cell neuroendocrine carcinoma of the skin as a distinct histological category. The patients are a 63-year-old woman with a 7-mm reddish round nodule on her nose for 4 months, and a 95-year-old man with several hemorrhagic nodules on the external ear for 28 months. The first patient had two positive sentinel lymph nodes. The tumors from both patients consisted of islands of pleomorphic large cells within a lymphoid stroma.
- Subjects :
- Aged, 80 and over
Biomarkers, Tumor metabolism
Carcinoma in Situ diagnosis
Carcinoma, Merkel Cell diagnosis
Carcinoma, Neuroendocrine metabolism
Carcinoma, Neuroendocrine therapy
Carcinoma, Squamous Cell diagnosis
Chemotherapy, Adjuvant
Combined Modality Therapy
Cytoplasmic Granules ultrastructure
Diagnosis, Differential
Disease-Free Survival
Female
Humans
Lymphatic Metastasis
Male
Middle Aged
Neurosecretory Systems metabolism
Neurosecretory Systems ultrastructure
Radiotherapy, Adjuvant
Skin Neoplasms metabolism
Skin Neoplasms therapy
Synaptophysin metabolism
Carcinoma, Large Cell secondary
Carcinoma, Neuroendocrine secondary
Lymphoid Tissue pathology
Skin Neoplasms pathology
Stromal Cells pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1533-0311
- Volume :
- 29
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The American Journal of dermatopathology
- Publication Type :
- Academic Journal
- Accession number :
- 18032958
- Full Text :
- https://doi.org/10.1097/DAD.0b013e318159b45e