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Topical administration of leukotriene antagonists in immunogenic keratitis.
- Source :
-
Ophthalmic research [Ophthalmic Res] 1991; Vol. 23 (6), pp. 330-4. - Publication Year :
- 1991
-
Abstract
- Antagonists of leukotriene D4 (LTD4), 3-[7-(2-n-propyl-3-hydroxy-4-acetyl- phenoxy)-propoxy-2-methyl-3,4-dihydro-4-8-n-propyl-2H-1-benzopyran- 2-yl]-propionic acid (SC-39070) and 7-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxy- propoxy]-4-methyl- 2-oxo-2H-1-benzopyran-3-acetic acid (FPL-60319) were locally administered to eyes of rabbits with immunogenic keratitis. The period of circular leukocyte infiltration (Wessely's ring) in the cornea was markedly decreased. Edema and neovascularization of the cornea were not influenced.
Details
- Language :
- English
- ISSN :
- 0030-3747
- Volume :
- 23
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Ophthalmic research
- Publication Type :
- Academic Journal
- Accession number :
- 1803314
- Full Text :
- https://doi.org/10.1159/000267130