[Establishment of chromatographic fingerprint and quality assessment on Sichuan native medicinal plant Alisma plantago-aquatica].

Authors :: Liu HC
Yang WY
Chen XF
Source :: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2007 Sep; Vol. 32 (18), pp. 1844-7.
Publication Year :: 2007
Abstract: Objective: To establish chromatographic fingerprint of Sichuan native medicinal plant Alisma plantago-aquatica by RP-HPLC for the quality control.<br />Method: The gradient elution mode was applied in chromatographic separation, and data were analyzed by "Computer Aided Similarity Evaluation" software to compare the quality of A. plantago-aquatica samples from different habitats.<br />Result: The HPLC chromatographic fingerprinting of A. plantago-aquatica with 26 characteristic peaks was established from 17 lots of A. plantago-aquatica samples, peak 16 and 22 were identified as 24-acetyl alisol A and 23-acetyl alisol B, respectively.<br />Conclusion: The chromatographic fingerprinting of A. plantago-aquatica with high specificity can be used to control its quality and assure lot to lot consistency. The RP-HPLC fingerprint method is repeatable, feasible in analysis of A. plantago-aquatica.

Subjects :: China
Cholestenones standards
Drugs, Chinese Herbal analysis
Drugs, Chinese Herbal standards
Plant Roots chemistry
Quality Control
Reproducibility of Results
Alisma chemistry
Cholestenones analysis
Chromatography, High Pressure Liquid methods
Plants, Medicinal chemistry

Language :: Chinese
ISSN :: 1001-5302
Volume :: 32
Issue :: 18
Database :: MEDLINE
Journal :: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :: Academic Journal
Accession number :: 18051885

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