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Identification of regions of the SV40 genome which contain preferred SV40 T antigen-binding sites.

Authors :
Jessel D
Landau T
Hudson J
Lalor T
Tenen D
Livingston DM
Source :
Cell [Cell] 1976 Aug; Vol. 8 (4), pp. 535-45.
Publication Year :
1976

Abstract

SV40 T antigen binds to SV40 DNA. Using a series of purified SV40 DNA restriction fragments, we have obtained evidence indicating that the antigen preferentially binds to three specific regions. These binding regions are contained within Endo R-Hin d(II + III) A, B, and C.

Details

Language :
English
ISSN :
0092-8674
Volume :
8
Issue :
4
Database :
MEDLINE
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
182383
Full Text :
https://doi.org/10.1016/0092-8674(76)90222-1