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Beyond chemotherapy--demystifying the new 'targeted' cancer treatments.
- Source :
-
Australian family physician [Aust Fam Physician] 2008 Jan-Feb; Vol. 37 (1-2), pp. 45-9. - Publication Year :
- 2008
-
Abstract
- It has been known for some time that key genetic changes are the principle mechanism of cancer development. These changes lead to abnormalities in the signalling pathways of cells and result in unregulated cell growth, angiogenesis and metastasis.
- Subjects :
- Antibodies, Monoclonal adverse effects
Antibodies, Monoclonal pharmacology
Antibodies, Monoclonal, Humanized
Antineoplastic Agents adverse effects
Benzamides
Drug Interactions
Humans
Imatinib Mesylate
Piperazines therapeutic use
Protein Kinase Inhibitors adverse effects
Protein Kinase Inhibitors pharmacology
Pyrimidines therapeutic use
Receptors, Vascular Endothelial Growth Factor physiology
Trastuzumab
Antibodies, Monoclonal therapeutic use
Antineoplastic Agents therapeutic use
ErbB Receptors antagonists & inhibitors
Molecular Biology trends
Neoplasms drug therapy
Protein Kinase Inhibitors therapeutic use
Receptors, Vascular Endothelial Growth Factor antagonists & inhibitors
Signal Transduction drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0300-8495
- Volume :
- 37
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Australian family physician
- Publication Type :
- Academic Journal
- Accession number :
- 18239753