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Vanishing bile duct syndrome.

Vanishing bile duct syndrome.

Authors :
Reau NS
Jensen DM
Source :
Clinics in liver disease [Clin Liver Dis] 2008 Feb; Vol. 12 (1), pp. 203-17, x.
Publication Year :
2008

Abstract

Perhaps no condition associated with chronic cholestasis is less understood than vanishing bile duct syndrome, a term that refers loosely to the group of acquired disorders associated with progressive destruction and disappearance of the intrahepatic bile ducts and, ultimately, cholestasis. Although the array of insults resulting in poor bile flow is vast, most adult patients who have chronic cholestasis have either primary biliary cirrhosis (or primary sclerosing cholangitis; in some cases, however, a cause cannot be identified. This article reviews the multiple causes, postulated pathophysiology, clinical features, and treatment options for this syndrome.

Details

Language :
English
ISSN :
1089-3261
Volume :
12
Issue :
1
Database :
MEDLINE
Journal :
Clinics in liver disease
Publication Type :
Academic Journal
Accession number :
18242505
Full Text :
https://doi.org/10.1016/j.cld.2007.11.007