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Unexpected occurrence of plasmid-mediated quinolone resistance determinants in environmental Aeromonas spp.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2008 Feb; Vol. 14 (2), pp. 231-7. - Publication Year :
- 2008
-
Abstract
- We searched for plasmid-mediated quinolone resistance determinants of the Qnr type in several water samples collected at diverse locations from the Seine River (Paris, France). The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A. media. The qnrS2 gene was located on IncU-type plasmids in both isolates, which resulted in increased MIC values of quinolones and fluoroquinolones, once they were transferred into Escherichia coli. The qnrS2 gene identified in A. punctata was part of novel genetic structure corresponding to a mobile insertion cassette element. This identification of plasmid-mediated qnr genes outside Enterobacteriaceae underlines a possible diffusion of those resistance determinants within gram-negative rods.
- Subjects :
- Aeromonas classification
Aeromonas genetics
Aeromonas isolation & purification
Fluoroquinolones pharmacology
Microbial Sensitivity Tests
Paris
Aeromonas drug effects
Anti-Bacterial Agents pharmacology
Bacterial Proteins genetics
Drug Resistance, Bacterial genetics
Plasmids genetics
Quinolones pharmacology
Rivers microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6040
- Volume :
- 14
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 18258115
- Full Text :
- https://doi.org/10.3201/eid1402.070677