Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues.

Subjects

Subjects :

Administration, Oral
Animals
Biological Availability
Caco-2 Cells
Humans
Methylation
Models, Molecular
Molecular Structure
Rats
Somatostatin administration & dosage
Somatostatin chemistry
Somatostatin analogs & derivatives
Somatostatin pharmacokinetics

Details

Language :

English

ISSN :

1521-3773

Volume :

47

Issue :

14

Database :

MEDLINE

Journal :

Angewandte Chemie (International ed. in English)

Publication Type :

Academic Journal

Accession number :

18297660

Full Text :

https://doi.org/10.1002/anie.200705797