Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation.

Authors :: Kaiser C
Segui-Lines G
D'Amaral JC
Ptolemy AS
Britz-McKibbin P
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2008 Jan 21 (3), pp. 338-40.
Publication Year :: 2008
Abstract: Electrokinetic probes based on the differential migration of ternary boronate ester complexes permit the selective analysis of micromolar levels of UV-transparent polyol stereoisomers in urine samples via dynamic complexation-capillary electrophoresis that is applicable to single-step screening of in-born errors of sugar metabolism, such as galactosemia.

Subjects :: Buffers
Electrochemistry
Electrophoresis, Capillary
Galactosemias urine
Humans
Infant, Newborn
Molecular Structure
Sensitivity and Specificity
Stereoisomerism
Boronic Acids chemistry
Molecular Probes chemistry
Sugar Alcohols urine

Full Text Access

Tools