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Predictors of postacute mortality following traumatic brain injury in a seriously injured population.
- Source :
-
The Journal of trauma [J Trauma] 2008 Apr; Vol. 64 (4), pp. 876-82. - Publication Year :
- 2008
-
Abstract
- Background: Traumatic brain injury (TBI) is a primary cause of injury mortality in developed countries but less is known about the impact of TBI on postacute mortality in large study populations. This study investigates the rate and predictors of postacute mortality (1-9 years after the initial injury) of severely injured persons with TBI in the Province of Ontario from April 1, 1993 to March 31, 1995.<br />Method: Cases were identified (n = 2,721) from the Ontario Trauma Registry Comprehensive Data Set based on lead trauma hospitals in the province which also provided data on predictors. Severely injured patients (n = 557) who had lower extremity injuries during the sample time period formed a control population.<br />Results: Poisson regression modeling showed that having a TBI was a significant predictor of premature death controlling for age and injury severity. Age, the number of comorbidities, injury severity, mechanism of injury, and discharge destination were significant predictors in the multivariate analyses for the TBI population.<br />Conclusions: This research quantifies the elevated risk of premature death in the postacute period for seriously injured adults with TBI and identifies factors most associated with highest mortality rates in this population.
- Subjects :
- Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Analysis of Variance
Brain Injuries therapy
Cohort Studies
Combined Modality Therapy
Female
Glasgow Coma Scale
Humans
Incidence
Injury Severity Score
Male
Middle Aged
Ontario epidemiology
Poisson Distribution
Predictive Value of Tests
Registries
Retrospective Studies
Risk Assessment
Sex Distribution
Survival Analysis
Time Factors
Brain Injuries diagnosis
Brain Injuries mortality
Cause of Death
Hospital Mortality trends
Subjects
Details
- Language :
- English
- ISSN :
- 1529-8809
- Volume :
- 64
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Journal of trauma
- Publication Type :
- Academic Journal
- Accession number :
- 18404051
- Full Text :
- https://doi.org/10.1097/TA.0b013e31804d493e