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Biofilms and their role in otorhinolaryngological disease.
- Source :
-
The Journal of laryngology and otology [J Laryngol Otol] 2008 Dec; Vol. 122 (12), pp. 1273-8. Date of Electronic Publication: 2008 Apr 11. - Publication Year :
- 2008
-
Abstract
- Objective: To describe the pathophysiology of biofilm communities and their role in otorhinolaryngological disease, with reference to the published literature.<br />Design: Review of relevant literature, using Medline and the combined search terms 'biofilms' and 'otorhinolaryngology', and also various related keywords such as 'tonsil' and 'adenoid'.<br />Results: Description of biofilm pathophysiology and of published reports of biofilms in otorhinolaryngological disease.<br />Conclusion: Virtually all microbes live in biofilm communities. Within these communities, the microbes assume differing specialised roles which confer survival advantages on the community. These communities cause chronic and device-associated infections. Within the specialist field of otorhinolaryngology, biofilms have been shown to play a role in many infections, including: chronic otitis media, cholesteatoma, chronic tonsillitis, chronic sinusitis, and infections of tracheostomies, endotracheal tubes and cochlear implants.
- Subjects :
- Anti-Bacterial Agents therapeutic use
Bacterial Adhesion physiology
Bacterial Infections drug therapy
Chronic Disease
Female
Humans
Male
Otorhinolaryngologic Diseases drug therapy
Phenotype
Prosthesis-Related Infections drug therapy
Risk Factors
Bacterial Infections microbiology
Biofilms growth & development
Otorhinolaryngologic Diseases microbiology
Prosthesis-Related Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1748-5460
- Volume :
- 122
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of laryngology and otology
- Publication Type :
- Academic Journal
- Accession number :
- 18405407
- Full Text :
- https://doi.org/10.1017/S0022215108002193