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EpiToolKit--a web server for computational immunomics.

Authors :
Feldhahn M
Thiel P
Schuler MM
Hillen N
Stevanovic S
Rammensee HG
Kohlbacher O
Source :
Nucleic acids research [Nucleic Acids Res] 2008 Jul 01; Vol. 36 (Web Server issue), pp. W519-22. Date of Electronic Publication: 2008 Apr 24.
Publication Year :
2008

Abstract

Predicting the T-cell-mediated immune response is an important task in vaccine design and thus one of the key problems in computational immunomics. Various methods have been developed during the last decade and are available online. We present EpiToolKit, a web server that has been specifically designed to offer a problem-solving environment for computational immunomics. EpiToolKit offers a variety of different prediction methods for major histocompatibility complex class I and II ligands as well as minor histocompatibility antigens. These predictions are embedded in a user-friendly interface allowing refining, editing and constraining the searches conveniently. We illustrate the value of the approach with a set of novel tumor-associated peptides. EpiToolKit is available online at www.epitoolkit.org.

Details

Language :
English
ISSN :
1362-4962
Volume :
36
Issue :
Web Server issue
Database :
MEDLINE
Journal :
Nucleic acids research
Publication Type :
Academic Journal
Accession number :
18440979
Full Text :
https://doi.org/10.1093/nar/gkn229