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Prognostic impact of thrombocytosis in resectable non-small cell lung cancer.
- Source :
-
Interactive cardiovascular and thoracic surgery [Interact Cardiovasc Thorac Surg] 2008 Aug; Vol. 7 (4), pp. 613-5. Date of Electronic Publication: 2008 May 23. - Publication Year :
- 2008
-
Abstract
- Relationship between thrombocytosis and poor prognosis has been reported in lung cancer. However, the majority of previous studies included many advanced stage and small cell lung cancer patients. Few studies focused on resectable non-small cell lung cancer patients. In the present study, therefore, consecutive 240 non-small cell lung cancer patients who received surgical resection were reviewed retrospectively, and investigated the survival impact of preoperative platelet count. In our results, the frequency of preoperative thrombocytosis was only 5.83% (14/240). The 5-year survival of patients with and without thrombocytosis was 28.87% and 63.73%, respectively. Both univariate and multivariate analyses indicated the independent prognostic impact of thrombocytosis. The present study is the first evaluation of prognostic effect of thrombocytosis in patients with resectable non-small cell lung cancer. Preoperative platelet count was a prognostic factor for resectable non-small cell lung cancer patients.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung blood
Carcinoma, Non-Small-Cell Lung complications
Carcinoma, Non-Small-Cell Lung mortality
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Platelet Count
Retrospective Studies
Thrombocytosis blood
Thrombocytosis mortality
Time Factors
Treatment Outcome
Carcinoma, Non-Small-Cell Lung surgery
Lung Neoplasms surgery
Pneumonectomy
Thrombocytosis complications
Subjects
Details
- Language :
- English
- ISSN :
- 1569-9285
- Volume :
- 7
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Interactive cardiovascular and thoracic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 18502783
- Full Text :
- https://doi.org/10.1510/icvts.2007.174391