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Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: cost utility analysis alongside a randomised controlled trial.
- Source :
-
BMJ (Clinical research ed.) [BMJ] 2008 Jun 14; Vol. 336 (7657), pp. 1351-4. Date of Electronic Publication: 2008 May 23. - Publication Year :
- 2008
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Abstract
- Objective: To determine whether the faster recovery after early surgery for sciatica compared with prolonged conservative care is attained at reasonable costs.<br />Design: Cost utility analysis alongside a randomised controlled trial.<br />Setting: Nine Dutch hospitals.<br />Participants: 283 patients with sciatica for 6-12 weeks, caused by lumbar disc herniation.<br />Interventions: Six months of prolonged conservative care compared with early surgery.<br />Main Outcome Measures: Quality adjusted life years (QALYs) at one year and societal costs, estimated from patient reported utilities (UK and US EuroQol, SF-6D, and visual analogue scale) and diaries on costs (healthcare, patient's costs, and productivity).<br />Results: Compared with prolonged conservative care, early surgery provided faster recovery, with a gain in QALYs according to the UK EuroQol of 0.044 (95% confidence interval 0.005 to 0.083), the US EuroQol of 0.032 (0.005 to 0.059), the SF-6D of 0.024 (0.003 to 0.046), and the visual analogue scale of 0.032 (-0.003 to 0.066). From the healthcare perspective, early surgery resulted in higher costs (difference euro1819 (pound1449; $2832), 95% confidence interval euro842 to euro2790), with a cost utility ratio per QALY of euro41 000 (euro14,000 to euro430 000). From the societal perspective, savings on productivity costs led to a negligible total difference in cost (euro-12, euro-4029 to euro4006).<br />Conclusions: Faster recovery from sciatica makes early surgery likely to be cost effective compared with prolonged conservative care. The estimated difference in healthcare costs was acceptable and was compensated for by the difference in absenteeism from work. For a willingness to pay of euro40,000 or more per QALY, early surgery need not be withheld for economic reasons. Trial registration Current Controlled Trials ISRCTN 26872154.
- Subjects :
- Adolescent
Adult
Aged
Cost-Benefit Analysis
Health Care Costs
Humans
Intervertebral Disc Displacement complications
Intervertebral Disc Displacement economics
Middle Aged
Netherlands
Quality-Adjusted Life Years
Sciatica economics
Sciatica etiology
Intervertebral Disc Displacement surgery
Sciatica surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1756-1833
- Volume :
- 336
- Issue :
- 7657
- Database :
- MEDLINE
- Journal :
- BMJ (Clinical research ed.)
- Publication Type :
- Academic Journal
- Accession number :
- 18502912
- Full Text :
- https://doi.org/10.1136/bmj.39583.709074.BE