Cytomegalovirus retinitis and immune recovery uveitis in AIDS patients treated with highly active antiretroviral therapy in Taiwanese.

Authors :: Lin YC
Yang CH
Lin CP
Yang CM
Chen MS
Chen MY
Sheng WH
Hung CC
Chang SC
Source :: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2008 May-Jun; Vol. 16 (3), pp. 83-7.
Publication Year :: 2008
Abstract: Purpose: To determine the characteristics of cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU) in the era of highly active antiretroviral therapy (HAART).<br />Methods: We reviewed data from 47 of 79 consecutive patients with acquired immunodeficiency syndrome (AIDS) and CMV retinitis.<br />Results: The incidence of CMV retinitis in AIDS patients has markedly decreased over the recent 10 years. The characteristics of CMV retinitis have changed. Development of IRU occurred in 24.4%.<br />Conclusions: Symptomatic IRU develops in a significant number of patients with inactive CMV retinitis following successful HAART. Eyes with IRU respond favorably to antiinflammatory therapy without reactivation of retinitis.

Subjects :: Acquired Immunodeficiency Syndrome drug therapy
Acquired Immunodeficiency Syndrome ethnology
Adult
Female
Humans
Incidence
Male
Middle Aged
Recovery of Function
Retrospective Studies
Taiwan epidemiology
Uveitis immunology
Acquired Immunodeficiency Syndrome complications
Acquired Immunodeficiency Syndrome physiopathology
Antiretroviral Therapy, Highly Active
Cytomegalovirus Retinitis complications
Cytomegalovirus Retinitis epidemiology
Immune System physiopathology
Uveitis etiology

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