Conversion of oximes to carbonyl compounds by triscetylpyridinium tetrakis(oxodiperoxotungsto) phosphate (PCWP)-mediated oxidation with hydrogen peroxide.

Authors :: Ballistreri FP
Chiacchio U
Rescifina A
Tomaselli G
Toscano RM
Source :: Molecules (Basel, Switzerland) [Molecules] 2008 Jun 01; Vol. 13 (6), pp. 1230-7. Date of Electronic Publication: 2008 Jun 01.
Publication Year :: 2008
Abstract: Aromatic and aliphatic oximes have been deoximated in chloroform-water to the corresponding aldehydes with dilute hydrogen peroxide and triscetylpyridinium tetrakis (oxodiperoxotungsto) phosphate as catalyst. The presence of dipolarophiles in the reaction mixtures allows a competitive reaction that converts oximes into isoxazole and isoxazoline derivatives via the intermediate formation of nitrile oxide species.

Subjects :: Isoxazoles chemical synthesis
Organic Chemicals chemical synthesis
Oxidation-Reduction
Aldehydes chemical synthesis
Hydrogen Peroxide chemistry
Oximes chemistry

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