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Construction of a versatile high precision ambient ionization source for direct analysis and imaging.
- Source :
-
Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2008 Oct; Vol. 19 (10), pp. 1527-34. Date of Electronic Publication: 2008 Jun 28. - Publication Year :
- 2008
-
Abstract
- The design and construction of a high precision ambient ionization source matrix-assisted laser desorption electrospray ionization (MALDESI) are described in full detail, including a complete parts list. The computer controlled high precision motion control system and high repetition rate Explorer laser are demonstrated during MALDESI-FT-ICR analysis of peptides and proteins ranging from 1 to 17 kDa. The high stability ionization source platform described herein demonstrates both the advantages of the new MALDESI source and versatility for application to numerous desorption and ionization techniques.
- Subjects :
- Bradykinin chemistry
Humans
Lasers
Melitten chemistry
Muramidase chemistry
Myoglobin chemistry
Spectrometry, Mass, Electrospray Ionization methods
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization methods
Ubiquitin chemistry
Cations chemistry
Spectrometry, Mass, Electrospray Ionization instrumentation
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization instrumentation
Subjects
Details
- Language :
- English
- ISSN :
- 1044-0305
- Volume :
- 19
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of the American Society for Mass Spectrometry
- Publication Type :
- Academic Journal
- Accession number :
- 18657438
- Full Text :
- https://doi.org/10.1016/j.jasms.2008.06.013