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Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity.

Authors :
Balan AM
Florea O
Moldoveanu C
Zbancioc G
Iurea D
Mangalagiu II
Source :
European journal of medicinal chemistry [Eur J Med Chem] 2009 May; Vol. 44 (5), pp. 2275-9. Date of Electronic Publication: 2008 Jun 26.
Publication Year :
2009

Abstract

Herein we report a feasible study concerning syntheses, structure and antimicrobial activity of some new diazinium salts with dihydroxyacetophenone skeleton. A fast, general, environmentally friendly, and facile method for preparation of diazinium salts under microwave and ultrasounds irradiation is presented. Antimicrobial tests prove that some diazine compounds have a remarkable activity against different microorganisms (germs and fungi), the pyrimidine derivatives being more active. Correlations between structure and antimicrobial activity are reported.

Details

Language :
English
ISSN :
1768-3254
Volume :
44
Issue :
5
Database :
MEDLINE
Journal :
European journal of medicinal chemistry
Publication Type :
Academic Journal
Accession number :
18672317
Full Text :
https://doi.org/10.1016/j.ejmech.2008.06.017