Back to Search
Start Over
Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity.
- Source :
-
European journal of medicinal chemistry [Eur J Med Chem] 2009 May; Vol. 44 (5), pp. 2275-9. Date of Electronic Publication: 2008 Jun 26. - Publication Year :
- 2009
-
Abstract
- Herein we report a feasible study concerning syntheses, structure and antimicrobial activity of some new diazinium salts with dihydroxyacetophenone skeleton. A fast, general, environmentally friendly, and facile method for preparation of diazinium salts under microwave and ultrasounds irradiation is presented. Antimicrobial tests prove that some diazine compounds have a remarkable activity against different microorganisms (germs and fungi), the pyrimidine derivatives being more active. Correlations between structure and antimicrobial activity are reported.
- Subjects :
- Acetophenones pharmacology
Anti-Bacterial Agents pharmacology
Antifungal Agents pharmacology
Feasibility Studies
Green Chemistry Technology
Microbial Sensitivity Tests
Microwaves
Structure-Activity Relationship
Acetophenones chemical synthesis
Anti-Bacterial Agents chemical synthesis
Antifungal Agents chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1768-3254
- Volume :
- 44
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- European journal of medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 18672317
- Full Text :
- https://doi.org/10.1016/j.ejmech.2008.06.017