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[Chromosome 17 abnormalities in medulloblastomas and their prognostic value].
- Source :
-
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2008 Apr-Jun (2), pp. 3-5; discussion 5. - Publication Year :
- 2008
-
Abstract
- The cytogenetic profile of chromosome 17 was studied in 180 medlloblastomas by the interphasic FISH technique, which revealed the high incidence of this aberration and its association with the poor clinical course of the disease. The interphasic cytogenetic analysis of chromosome 17 abnormalities in medulloblastoma biopsy specimens may be recommended for its inclusion into a complex of laboratory diagnostic methods used in the examination of these tumors.
- Subjects :
- Adolescent
Adult
Cerebellar Neoplasms epidemiology
Cerebellar Neoplasms therapy
Female
Humans
In Situ Hybridization, Fluorescence
Kaplan-Meier Estimate
Male
Medulloblastoma epidemiology
Medulloblastoma therapy
Predictive Value of Tests
Cerebellar Neoplasms genetics
Chromosome Aberrations
Chromosomes, Human, Pair 17 genetics
Medulloblastoma genetics
Subjects
Details
- Language :
- Russian
- ISSN :
- 0042-8817
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
- Publication Type :
- Academic Journal
- Accession number :
- 18724421