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[Chromosome 17 abnormalities in medulloblastomas and their prognostic value].

Authors :
Korshunov AG
Sycheva RV
Gorelyshev SK
Ozerov SS
Golanov AV
Source :
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] 2008 Apr-Jun (2), pp. 3-5; discussion 5.
Publication Year :
2008

Abstract

The cytogenetic profile of chromosome 17 was studied in 180 medlloblastomas by the interphasic FISH technique, which revealed the high incidence of this aberration and its association with the poor clinical course of the disease. The interphasic cytogenetic analysis of chromosome 17 abnormalities in medulloblastoma biopsy specimens may be recommended for its inclusion into a complex of laboratory diagnostic methods used in the examination of these tumors.

Details

Language :
Russian
ISSN :
0042-8817
Issue :
2
Database :
MEDLINE
Journal :
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
Publication Type :
Academic Journal
Accession number :
18724421