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Asymmetric Pauson-Khand-type reaction mediated by Rh(I) catalyst at ambient temperature.

Authors :
Kim DE
Kim IS
Ratovelomanana-Vidal V
GenĂȘt JP
Jeong N
Source :
The Journal of organic chemistry [J Org Chem] 2008 Oct 17; Vol. 73 (20), pp. 7985-9. Date of Electronic Publication: 2008 Sep 18.
Publication Year :
2008

Abstract

An efficient asymmetric PKR mediated by Rh(I) catalyst at ambient temperature was developed. The reaction utilizing a Rh(I) catalyst bearing a (R)-3,5-diMeC4H4-BINAP ligand at 18-20 degrees C under a reduced partial pressure of CO (0.1 atm) provided PKR products in high chemical yield as well as high enantioselectivity.

Details

Language :
English
ISSN :
1520-6904
Volume :
73
Issue :
20
Database :
MEDLINE
Journal :
The Journal of organic chemistry
Publication Type :
Academic Journal
Accession number :
18798672
Full Text :
https://doi.org/10.1021/jo801236c