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The electroretinogram (ERG) of a diurnal cone-rich laboratory rodent, the Nile grass rat (Arvicanthis niloticus).
- Source :
-
Vision research [Vision Res] 2008 Dec; Vol. 48 (27), pp. 2723-31. Date of Electronic Publication: 2008 Oct 19. - Publication Year :
- 2008
-
Abstract
- The most widespread models to study blindness, rats and mice, have retinas containing less than 3% cones. The diurnal rodent Arvicanthis niloticus retina has around 35% cones. Using ERG recordings, we studied retina function in this species. Several features differed from that reported in rats and mice: (a) fivefold larger photopic a-wave amplitudes; (b) photopic hill effect in Nile grass rats only; and (c) flicker amplitude plateau between 5 to 35 Hz with fusion beyond 60 Hz in Nile grass rats only. We conclude that A. niloticus might complement rats and mice for studying retinal function and pathologies involving cones.
- Subjects :
- Adult
Animals
Dark Adaptation physiology
Disease Models, Animal
Electroretinography
Female
Humans
Male
Middle Aged
Muridae anatomy & histology
Photic Stimulation methods
Retinal Cone Photoreceptor Cells cytology
Sensory Thresholds physiology
Species Specificity
Young Adult
Circadian Rhythm physiology
Muridae physiology
Retinal Cone Photoreceptor Cells physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-5646
- Volume :
- 48
- Issue :
- 27
- Database :
- MEDLINE
- Journal :
- Vision research
- Publication Type :
- Academic Journal
- Accession number :
- 18824014
- Full Text :
- https://doi.org/10.1016/j.visres.2008.09.004