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Imipenem resistance in pseudomonas aeruginosa PAO: mapping of the OprD2 gene.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 1991 Apr; Vol. 35 (4), pp. 753-5. - Publication Year :
- 1991
-
Abstract
- Carbapenem antibiotics have been shown to penetrate the outer membrane of Pseudomonas aeruginosa through a unique porin protein, OprD2. We mapped the OprD2 gene by conjugation using plasmid FP2 and by transduction using phage F116L. This gene maps between 71 and 75 min on the PAO1 chromosome.
- Subjects :
- Bacterial Outer Membrane Proteins biosynthesis
Bacterial Outer Membrane Proteins genetics
Bacteriophages
Chromosome Mapping
Culture Media
Drug Resistance, Microbial
Electrophoresis, Polyacrylamide Gel
Mutation
Plasmids
Pseudomonas aeruginosa genetics
Transduction, Genetic
Imipenem pharmacology
Pseudomonas aeruginosa drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0066-4804
- Volume :
- 35
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 1906263
- Full Text :
- https://doi.org/10.1128/AAC.35.4.753