Rosette formation by human T and B lymphocytes in the presence of adrenergic and cholinergic drugs.

Authors :: Ferreira GG
Brascher HK
Javierre MQ
Sassine WA
Lima AO
Source :: Experientia [Experientia] 1976 Dec 15; Vol. 32 (12), pp. 1594-6.
Publication Year :: 1976
Abstract: It was shown that adrenergic drugs, which increase the intracellular levels of cAMP, inhibit the rosette formation by T-lymphocytes, but stimulate the rosettes produced by B-lymphocytes. Cholinergic drugs, which increase the levels of cGMP, on the contrary, stimulate the formation of rosettes by T-lymphocytes but inhibit those produced by B-lymphocytes.

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