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Initializing partition-optimization algorithms.

Authors :
Maitra R
Source :
IEEE/ACM transactions on computational biology and bioinformatics [IEEE/ACM Trans Comput Biol Bioinform] 2009 Jan-Mar; Vol. 6 (1), pp. 144-57.
Publication Year :
2009

Abstract

Clustering datasets is a challenging problem needed in a wide array of applications. Partition-optimization approaches, such as k-means or expectation-maximization (EM) algorithms, are sub-optimal and find solutions in the vicinity of their initialization. This paper proposes a staged approach to specifying initial values by finding a large number of local modes and then obtaining representatives from the most separated ones. Results on test experiments are excellent. We also provide a detailed comparative assessment of the suggested algorithm with many commonly-used initialization approaches in the literature. Finally, the methodology is applied to two datasets on diurnal microarray gene expressions and industrial releases of mercury.

Details

Language :
English
ISSN :
1557-9964
Volume :
6
Issue :
1
Database :
MEDLINE
Journal :
IEEE/ACM transactions on computational biology and bioinformatics
Publication Type :
Academic Journal
Accession number :
19179708
Full Text :
https://doi.org/10.1109/TCBB.2007.70244