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[Oncogenic osteomalacia: localization of underlying peripheral tumor with 99mTc-sestamibi scintigraphy].
- Source :
-
Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2008 Dec; Vol. 52 (9), pp. 1505-9. - Publication Year :
- 2008
-
Abstract
- Oncogenic osteomalacia is a paraneoplastic syndrome usually induced by bone or soft tissue tumors. It is presented by the development of pain and fractures with hypophosphatemia, hyperphosphaturia, and inappropriate normal/low plasma 1,25(OH)2D3 concentration. After the removal of the tumor the complete resolution of all biochemical and clinical abnormalities is the main characteristic. A case of a 44-year-old female with difficulty in walking due to leg pain and generalized muscle weakness and hypophosphatemia, with relative hyperphosphaturia, is described. A whole-body 99mTc-sestamibi scintigraphy showed accumulation in the left thigh region, and a small tumor was detected by ultrasound examination. By removal of the tumor, a lipoma, the symptoms improved significantly after a month, with complete recovery by the fourth month. In this case, 99mTc-sestamibi scintigraphy was useful in identifying the location of the tumor, which caused oncogenic osteomalacia.
Details
- Language :
- Portuguese
- ISSN :
- 1677-9487
- Volume :
- 52
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Arquivos brasileiros de endocrinologia e metabologia
- Publication Type :
- Academic Journal
- Accession number :
- 19197461
- Full Text :
- https://doi.org/10.1590/s0004-27302008000900016