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[Progress in child epilepsy].
- Source :
-
La Tunisie medicale [Tunis Med] 2008 Nov; Vol. 86 (11), pp. 960-2. - Publication Year :
- 2008
-
Abstract
- Child epilepsy continues to concern the researchers and the clinicians and carried out these last years of important progress as well in the genetic field, as in physiopathology, clinic and therapeutic one. The identification of new genes of epilepsy, epilepsies related to channelopathy and new phenotypes related to precise genetic mutations, constitutes a major progress of paediatric epilepsy. The debate around the role of febrile convulsions in the development of hippocampal sclerosis is started again thanks to Diffusion MRI techniques. In utero exposure to antiepileptic drugs (AED), and its effects on neurodevelopment, is a very active field of research. An exposure to a polytherapy or to valproate would increase the risk of development delay. The ketogenic diet could be an alternative therapeutic during refractory epilepsies but can have serious consequences on the growth. Temporal lobe surgery is a good therapeutic option for refractory epilepsies of the child and offers, to him, better chances of social integration.
- Subjects :
- Age of Onset
Anticonvulsants therapeutic use
Child
Chromosomes, Human, Pair 20 genetics
Diet, Ketogenic methods
Epilepsy diagnosis
Epilepsy diet therapy
Epilepsy drug therapy
Epilepsy genetics
Epilepsy surgery
Evidence-Based Medicine
Humans
Mutation
Phenotype
Risk Factors
Seizures, Febrile complications
Temporal Lobe surgery
Treatment Outcome
Epilepsy therapy
Subjects
Details
- Language :
- French
- ISSN :
- 0041-4131
- Volume :
- 86
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- La Tunisie medicale
- Publication Type :
- Academic Journal
- Accession number :
- 19213485