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The assessment of residual kidney function after living donor nephrectomy.
- Source :
-
Transplantation proceedings [Transplant Proc] 2009 Jan-Feb; Vol. 41 (1), pp. 91-2. - Publication Year :
- 2009
-
Abstract
- Background: The number of patients on the waiting list for kidney transplantation is increasing as a result of the cadaveric donor shortage. One way to expand the pool is living donor transplantation. However, only 2% of kidney transplants in Poland come from living-related donors.<br />Aim: We sought to assess residual renal function, incidence of hypertension, and proteinuria among living kidney donors.<br />Patients and Methods: Between 2004 and 2007, we performed 46 living donor open nephrectomies. The mean age of the kidney donor was 39 years (range, 25-57). The donors were predominantly females (61%). Mean hospitalization time was 8 days (range, 4-22). Nine donors did not report for follow-up visits. The observation periods ranged from 1 to 24 months. Physical examination, blood and urine tests, as well as ultrasound scans were performed before nephrectomy and at every follow-up visit (1, 3, 12, and 24 months post operatively).<br />Results: Mean creatinine concentration was higher at 3 months after nephrectomy than preoperatively (P < .05). Mean creatinine clearance according to Cockroft-Gault formula and mean creatinine clearance according to abbreviated modification of diet in renal disease equation (aMDRD) decreased after donation by 30% (P < .05). No cases of proteinuria were observed. Hypertension occurred in 1 donor (2.7%).<br />Conclusion: Living kidney donation resulted in a reduced creatinine clearance in the donor. Follow-up of living kidney donors is essential to determine risk factors for deterioration of residual kidney function.
- Subjects :
- Adult
Body Mass Index
Creatinine blood
Family
Female
Follow-Up Studies
Humans
Hypertension epidemiology
Length of Stay
Male
Middle Aged
Poland
Postoperative Complications epidemiology
Proteinuria epidemiology
Siblings
Tissue Donors supply & distribution
Kidney Function Tests
Living Donors
Nephrectomy methods
Tissue and Organ Harvesting methods
Subjects
Details
- Language :
- English
- ISSN :
- 0041-1345
- Volume :
- 41
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 19249485
- Full Text :
- https://doi.org/10.1016/j.transproceed.2008.08.160