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The evolving understanding of COPI vesicle formation.
- Source :
-
Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2009 May; Vol. 10 (5), pp. 360-4. Date of Electronic Publication: 2009 Mar 18. - Publication Year :
- 2009
-
Abstract
- The coat protein I (COPI) complex is considered to be one of the best-characterized coat complexes. Studies on how it functions in vesicle formation have provided seminal contributions to the general paradigm in vesicular transport that the ADP-ribosylation factor (ARF) small GTPases are key regulators of coat complexes. Here, we discuss emerging evidence that suggests the need to revise some long-held views on how COPI vesicle formation is achieved.
Details
- Language :
- English
- ISSN :
- 1471-0080
- Volume :
- 10
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Nature reviews. Molecular cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 19293819
- Full Text :
- https://doi.org/10.1038/nrm2663