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[Mitochondrial diabetes: clinical features, diagnosis and management].
- Source :
-
La Revue de medecine interne [Rev Med Interne] 2010 Mar; Vol. 31 (3), pp. 216-21. Date of Electronic Publication: 2009 Mar 18. - Publication Year :
- 2010
-
Abstract
- Mitochondrial diabetes affects up to 1% of patients with diabetes and is often unrecognised by the physicians. Maternally inherited diabetes and deafness (MIDD) resulting from the mutation 3243A>G of the mitochondrial DNA is the most frequent mutation associated with mitochondrial diabetes. This review summarizes the range of clinical phenotypes associated with MIDD and outlines the advances in genetic diagnosis, pathogenesis and management of these patients.<br /> (2009 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.)
- Subjects :
- Age of Onset
Deafness genetics
Diabetes Mellitus genetics
Genetic Predisposition to Disease
Genetic Testing
Genetic Variation
Genomic Imprinting
Humans
Mitochondrial Diseases diagnosis
Mitochondrial Diseases therapy
Pedigree
Phenotype
Retinal Diseases genetics
DNA, Mitochondrial genetics
Diabetes Mellitus diagnosis
Diabetes Mellitus therapy
Mitochondria genetics
Point Mutation
Subjects
Details
- Language :
- French
- ISSN :
- 1768-3122
- Volume :
- 31
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- La Revue de medecine interne
- Publication Type :
- Academic Journal
- Accession number :
- 19299044
- Full Text :
- https://doi.org/10.1016/j.revmed.2008.11.017