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Thrombus resolution and vein wall injury: dependence on chemokines and leukocytes.
- Source :
-
Thrombosis research [Thromb Res] 2009; Vol. 123 Suppl 4, pp. S72-8. - Publication Year :
- 2009
-
Abstract
- Chronic venous insufficiency resulting in post-thrombotic syndrome occurs commonly after acute deep vein thrombosis, and is a prevalent cause of vascular disease morbidity in the community. Therefore, a better understanding of the pathophysiologic mechanisms that promote the development of chronic venous insufficiency could lead to novel approaches to interrupt the natural history and prevent post-thrombotic syndrome. In this paper, we will review the evidence that venous thrombus resolution is an inflammatory process that is dependent on chemokines and leukocytes.
- Subjects :
- Cell Transdifferentiation
Chronic Disease
Humans
Inflammation complications
Inflammation pathology
Inflammation therapy
Intercellular Signaling Peptides and Proteins metabolism
Male
Matrix Metalloproteinases metabolism
Postthrombotic Syndrome pathology
Postthrombotic Syndrome prevention & control
Stem Cells immunology
Thrombosis complications
Thrombosis pathology
Thrombosis therapy
Veins pathology
Venous Insufficiency pathology
Venous Insufficiency prevention & control
Chemokines metabolism
Inflammation immunology
Leukocytes immunology
Postthrombotic Syndrome immunology
Thrombosis immunology
Veins immunology
Venous Insufficiency immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0049-3848
- Volume :
- 123 Suppl 4
- Database :
- MEDLINE
- Journal :
- Thrombosis research
- Publication Type :
- Academic Journal
- Accession number :
- 19303509
- Full Text :
- https://doi.org/10.1016/S0049-3848(09)70148-3