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Integration of motor proteins - towards an ATP fueled soft actuator.

Integration of motor proteins - towards an ATP fueled soft actuator.

Authors :
Kakugo A
Shikinaka K
Gong JP
Source :
International journal of molecular sciences [Int J Mol Sci] 2008 Sep; Vol. 9 (9), pp. 1685-1703. Date of Electronic Publication: 2008 Sep 04.
Publication Year :
2008

Abstract

We present a soft bio-machine constructed from biological motors (actin/myosin). We have found that chemically cross-linked polymer-actin complex gel filaments can move on myosin coated surfaces with a velocity as high as that of native F-actin, by coupling to ATP hydrolysis. Additionally, it is shown that the velocity of polymer-actin complex gel depends on the species of polycations binding to the F-actins. Since the design of functional actuators of well-defined size and morphology is important, the structural behavior of polymer-actin complexes has been investigated. Our results show that the morphology and growth size of polymer-actin complex can be controlled by changes in the electrostatic interactions between F-actins and polycations. Our results indicate that bio actuators with desired shapes can be created by using a polymer-actin complex.

Details

Language :
English
ISSN :
1422-0067
Volume :
9
Issue :
9
Database :
MEDLINE
Journal :
International journal of molecular sciences
Publication Type :
Academic Journal
Accession number :
19325826
Full Text :
https://doi.org/10.3390/ijms9091685