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B cell precursors are targets for Salmonella infection.

Authors :
Castro-Eguiluz D
Pelayo R
Rosales-Garcia V
Rosales-Reyes R
Alpuche-Aranda C
Ortiz-Navarrete V
Source :
Microbial pathogenesis [Microb Pathog] 2009 Jul; Vol. 47 (1), pp. 52-6. Date of Electronic Publication: 2009 Apr 19.
Publication Year :
2009

Abstract

We previously reported that, in mice, B cells are a reservoir for bacteria during Salmonella infection. Here, we show that, within the bone marrow, B cells and their precursors are targeted for infection by Salmonella enterica serovar typhimurium. Our data suggest that B cells within the bone marrow may be a bacterial niche during chronic Salmonella infection.

Details

Language :
English
ISSN :
1096-1208
Volume :
47
Issue :
1
Database :
MEDLINE
Journal :
Microbial pathogenesis
Publication Type :
Academic Journal
Accession number :
19383536
Full Text :
https://doi.org/10.1016/j.micpath.2009.04.005