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Protein folding in Escherichia coli: the chaperonin GroE and its substrates.

Authors :
Masters M
Blakely G
Coulson A
McLennan N
Yerko V
Acord J
Source :
Research in microbiology [Res Microbiol] 2009 May; Vol. 160 (4), pp. 267-77. Date of Electronic Publication: 2009 Apr 23.
Publication Year :
2009

Abstract

A brief summary of the role of DnaK and GroE chaperones in protein folding precedes a discussion of the role of GroE in Escherichia coli. We consider its obligate substrates, the 8 that are both obligate and essential, and the prospects for constructing a mutant that could survive without it. Structural features of GroE-dependent polypeptides are also considered.

Details

Language :
English
ISSN :
1769-7123
Volume :
160
Issue :
4
Database :
MEDLINE
Journal :
Research in microbiology
Publication Type :
Academic Journal
Accession number :
19393741
Full Text :
https://doi.org/10.1016/j.resmic.2009.04.002