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Functional mapping of the motor cortex of the rat using transdural electrical stimulation.

Functional mapping of the motor cortex of the rat using transdural electrical stimulation.

Authors :
Fonoff ET
Pereira JF Jr
Camargo LV
Dale CS
Pagano RL
Ballester G
Teixeira MJ
Source :
Behavioural brain research [Behav Brain Res] 2009 Aug 24; Vol. 202 (1), pp. 138-41. Date of Electronic Publication: 2009 Mar 24.
Publication Year :
2009

Abstract

Motor cortex stimulation oriented by functional cortical mapping is used mainly for treating otherwise intractable neurological disorders, however, its mechanism of action remains elusive. Herein, we present a new method for functional mapping of the rat motor cortex using non-invasive transdural electrical stimulation. This method allows a non-invasive mapping of the surface of the neocortex providing a differentiation of representative motor areas. This study may facilitate further investigation about the mechanisms mediating the effects of electrical stimulation, possibly benefiting patients who do not respond to this neuromodulation therapy.

Details

Language :
English
ISSN :
1872-7549
Volume :
202
Issue :
1
Database :
MEDLINE
Journal :
Behavioural brain research
Publication Type :
Academic Journal
Accession number :
19447290
Full Text :
https://doi.org/10.1016/j.bbr.2009.03.018