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Impulsive and compulsive behaviors in Parkinson's disease.
- Source :
-
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2009 Aug 15; Vol. 24 (11), pp. 1561-70. - Publication Year :
- 2009
-
Abstract
- Antiparkinson therapy can be the primary cause of a range of nonmotor symptoms that include a set of complex disinhibitory psychomotor pathologies and are linked by their repetitive, reward or incentive-based natures. These behaviors relate to aberrant or excessive dopamine receptor stimulation and encompass impulse control disorders (ICDs), punding, and the dopamine dysregulation syndrome (DDS). Common ICDs include pathological gambling, hypersexuality, compulsive eating, and compulsive buying. This review focuses on the phenomenology, epidemiology, and methods to identify and rate these disorders. The management of dopaminergic drug-related compulsive behaviors is discussed in the light of the current understanding of the neurobiological substrate of these disorders.<br /> (2009 Movement Disorder Society.)
- Subjects :
- Antiparkinson Agents therapeutic use
Compulsive Behavior epidemiology
Compulsive Behavior physiopathology
Deep Brain Stimulation
Disease Susceptibility
Dopamine physiology
Dopamine Agonists therapeutic use
Female
Gambling
Humans
Impulsive Behavior epidemiology
Impulsive Behavior physiopathology
Limbic System drug effects
Limbic System physiopathology
Male
Parkinson Disease drug therapy
Prevalence
Reward
Sexual Behavior drug effects
Stereotyped Behavior drug effects
Antiparkinson Agents adverse effects
Compulsive Behavior chemically induced
Dopamine Agonists adverse effects
Impulsive Behavior chemically induced
Parkinson Disease psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1531-8257
- Volume :
- 24
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Movement disorders : official journal of the Movement Disorder Society
- Publication Type :
- Academic Journal
- Accession number :
- 19526584
- Full Text :
- https://doi.org/10.1002/mds.22505