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[Determination of melamine and cyanuric acid in milk by gas chromatography-mass spectrometry].
- Source :
-
Se pu = Chinese journal of chromatography [Se Pu] 2009 Mar; Vol. 27 (2), pp. 233-6. - Publication Year :
- 2009
-
Abstract
- A gas chromatography-mass spectrometry method was developed for the quantitative determination and confirmation of melamine and cyanuric acid in milk. The milk sample was extracted with diethylamine-acetonitrile-water solution. The extract was evaporated to dryness and derivatized with N, O-bis (trimethylsilyl) trifluoroacetamide (BSTFA) and chlorotrimethylsilane (TMCS), then analyzed using gas chromatography-mass spectrometry (GC-MS) in selected ion monitoring (SIM) mode. The external standards were used for the quantitative determination. The linear range was from 0.025 to 2 mg/kg. The average recoveries were 84%-87% for melamine and 75%-102% for cyanuric acid, and the relative standard deviations were 5.7%-11.7% for melamine and 4.9%-7.8% for cyanuric acid in the spiked levels at 0.5, 1.0 and 2.5 mg/kg. The limits of detection of melamine and cyanuric acid were 0.05 mg/kg and 0.10 mg/kg, respectively. The method is suitable for the quantitative determination and confirmation of melainine and cyanuric acid residues in milk.
Details
- Language :
- Chinese
- ISSN :
- 1000-8713
- Volume :
- 27
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Se pu = Chinese journal of chromatography
- Publication Type :
- Academic Journal
- Accession number :
- 19626856