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A new triglucosylated naphthalene glycoside from Aloe vera L.
- Source :
-
Fitoterapia [Fitoterapia] 2010 Jan; Vol. 81 (1), pp. 59-62. Date of Electronic Publication: 2009 Jul 26. - Publication Year :
- 2010
-
Abstract
- A new triglucosylated naphthalene derivative, named aloveroside A (1), together with two known anthraquinone dimers and two 6-phenyl-2-pyrone derivatives, was isolated from the Aloe vera ethanolic extracts. The structure of 1 was established as 1-(((4-(1-O-beta-D-glucopyranosyl -(1-->4)-beta-D-xylopyranoside)-hydroxymethyl)-1-hydroxy-8-O-alpha-L-rhamnopyranoside)naphthalene-2-yl)-ethanone by means of spectroscopic evidences and chemical methods. All these compounds were tested for their BACE inhibitory activity but no significant activities were found.
- Subjects :
- Amyloid Precursor Protein Secretases antagonists & inhibitors
Drug Evaluation, Preclinical
Glycosides chemistry
Glycosides pharmacology
Molecular Structure
Naphthalenes chemistry
Naphthalenes pharmacology
Plant Extracts chemistry
Plant Extracts pharmacology
Aloe chemistry
Glycosides isolation & purification
Naphthalenes isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 81
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 19638305
- Full Text :
- https://doi.org/10.1016/j.fitote.2009.07.006