Back to Search
Start Over
Bilateral vestibular failure as an early sign in Creutzfeldt-Jakob disease.
- Source :
-
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2009 May; Vol. 1164, pp. 390-3. - Publication Year :
- 2009
-
Abstract
- Bilateral vestibular failure causes dysfunction of the vestibulo-ocular reflex with consecutive symptoms like apparent movements of the visual environment during head movements (oscillopsia) and unsteady gait in darkness or on uneven ground. A definite case of Creutzfeldt-Jakob disease in which bilateral vestibular loss was one of the first clinical signs is reported. Further, in a series of 9 consecutive patients with Creutzfeldt-Jakob disease (6 probable, 3 definite), 3 had bilateral vestibular loss at initial presentation. The vestibular nuclei are known to be severely affected in animal spongiform encephalopathies. They might also be a vulnerable target in human prion diseases.
Details
- Language :
- English
- ISSN :
- 1749-6632
- Volume :
- 1164
- Database :
- MEDLINE
- Journal :
- Annals of the New York Academy of Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 19645934
- Full Text :
- https://doi.org/10.1111/j.1749-6632.2008.03741.x