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[Expression of tryptase and chymase in human lung tissue of anaphylactic shock].
- Source :
-
Fa yi xue za zhi [Fa Yi Xue Za Zhi] 2009 Jun; Vol. 25 (3), pp. 164-7. - Publication Year :
- 2009
-
Abstract
- Objective: To explore the expression of tryptase and chymase in human lung tissue of anaphylactic shock and its value for forensic medicine.<br />Methods: With ten carbon monoxide poisoning cases as control group, the levels of tryptase and chymase were observed by immunofluorescence and analyzed using the Image Analyze and the Image-pro plus 5.0.2. The positive mast cells were counted and the levels of the tryptase and chymase were calculated respectively.<br />Results: There was a statistically significant difference (P < 0.05) for the tryptase and chymase concentrations in the lung tissue between the anaphylactic shock group and the control group.<br />Conclusion: The levels of the tryptase and the chymase expression are greatly increased in human lung tissue of anaphylactic shock, which may provide the morphological evidence and reference for the diagnosis of anaphylactic shock in forensic practice.
- Subjects :
- Adolescent
Adult
Anaphylaxis pathology
Cadaver
Carbon Monoxide Poisoning enzymology
Carbon Monoxide Poisoning pathology
Child
Child, Preschool
Female
Fluoroimmunoassay methods
Forensic Pathology
Humans
Infant
Lung pathology
Male
Middle Aged
Staining and Labeling
Young Adult
Anaphylaxis enzymology
Chymases metabolism
Lung enzymology
Mast Cells enzymology
Tryptases metabolism
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1004-5619
- Volume :
- 25
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Fa yi xue za zhi
- Publication Type :
- Academic Journal
- Accession number :
- 19697770