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Early onset obsessive-compulsive disorder with and without tics.
- Source :
-
CNS spectrums [CNS Spectr] 2009 Jul; Vol. 14 (7), pp. 362-70. - Publication Year :
- 2009
-
Abstract
- Introduction: Research suggests that obsessive-compulsive disorder (OCD) is not a unitary entity, but rather a highly heterogeneous condition, with complex and variable clinical manifestations.<br />Objective: The aims of this study were to compare clinical and demographic characteristics of OCD patients with early and late age of onset of obsessive-compulsive symptoms (OCS); and to compare the same features in early onset OCD with and without tics. The independent impact of age at onset and presence of tics on comorbidity patterns was investigated.<br />Methods: Three hundred and thirty consecutive outpatients meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for OCD were evaluated: 160 patients belonged to the "early onset" group (EOG): before 11 years of age, 75 patients had an "intermediate onset" (IOG), and 95 patients were from the "late onset" group (LOG): after 18 years of age. From the 160 EOG, 60 had comorbidity with tic disorders. The diagnostic instruments used were: the Yale-Brown Obsessive Compulsive Scale and the Dimensional Yale-Brown Obsessive Compulsive Scale (DY-BOCS), Yale Global Tics Severity Scale, and Structured Clinical Interview for DSM-IV Axis I Disorders-patient edition. Statistical tests used were: Mann-Whitney, full Bayesian significance test, and logistic regression.<br />Results: The EOG had a predominance of males, higher frequency of family history of OCS, higher mean scores on the "aggression/violence" and "miscellaneous" dimensions, and higher mean global DY-BOCS scores. Patients with EOG without tic disorders presented higher mean global DY-BOCS scores and higher mean scores in the "contamination/cleaning" dimension.<br />Conclusion: The current results disentangle some of the clinical overlap between early onset OCD with and without tics.
Details
- Language :
- English
- ISSN :
- 1092-8529
- Volume :
- 14
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- CNS spectrums
- Publication Type :
- Academic Journal
- Accession number :
- 19773712
- Full Text :
- https://doi.org/10.1017/s1092852900023014