Back to Search
Start Over
CTX-M and ampC beta-lactamases contributing to increased prevalence of ceftriaxone-resistant Escherichia coli in Changi General Hospital, Singapore.
- Source :
-
Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2010 Feb; Vol. 66 (2), pp. 210-3. Date of Electronic Publication: 2009 Oct 02. - Publication Year :
- 2010
-
Abstract
- Data from an 800-bed hospital showed an increase in the incidence density of ceftriaxone-resistant Escherichia coli, from 13.1 to 21.7 per 100 000 inpatient days over a 4-year period. Detailed testing performed on 54 E. coli isolates showed bla(CTX-M) extended-spectrum beta-lactamase (ESBL) genes (n = 37) and bla(CMY-like)ampC genes (n = 15). Typing data showed only limited clonal transmission in isolates with ESBL.<br /> (2010 Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Bacterial Typing Techniques
Cluster Analysis
DNA Fingerprinting
Electrophoresis, Gel, Pulsed-Field
Escherichia coli isolation & purification
Escherichia coli Infections microbiology
Female
Genotype
Hospitals, General
Humans
Male
Prevalence
Singapore
Anti-Bacterial Agents pharmacology
Ceftriaxone pharmacology
Drug Resistance, Bacterial
Escherichia coli drug effects
Escherichia coli enzymology
Escherichia coli Proteins biosynthesis
beta-Lactamases biosynthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0070
- Volume :
- 66
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Diagnostic microbiology and infectious disease
- Publication Type :
- Academic Journal
- Accession number :
- 19800752
- Full Text :
- https://doi.org/10.1016/j.diagmicrobio.2009.08.019