Back to Search
Start Over
Antibody response to influenza immunization in coronary artery disease patients: a controlled trial.
- Source :
-
Vaccine [Vaccine] 2009 Dec 10; Vol. 28 (1), pp. 110-3. Date of Electronic Publication: 2009 Oct 09. - Publication Year :
- 2009
-
Abstract
- Safety of and humoral immune response to the anti-influenza vaccine in coronary artery disease (CAD) patients were evaluated. The trivalent vaccine was administered to 137 eligible CAD patients and 67 age- and sex-matched healthy individuals. Antibody (Ab) titers were measured before and 1 month after vaccination. CAD and HC groups were not significantly different in serologic response and magnitude of change in antibody titers against each of the vaccine antigens. In multivariate analyses, regular exercise and using multivitamin supplements were independently associated with better antibody response among CAD patients. There were no major cardiac or general adverse effects. Influenza vaccine was found safe in CAD patients and antibody responses were similar to HCs.
- Subjects :
- Adult
Antibodies, Viral blood
Coronary Artery Disease virology
Female
Humans
Influenza Vaccines adverse effects
Influenza, Human immunology
Male
Middle Aged
Multivariate Analysis
Treatment Outcome
Antibody Formation immunology
Coronary Artery Disease immunology
Influenza Vaccines immunology
Influenza, Human prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2518
- Volume :
- 28
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 19819210
- Full Text :
- https://doi.org/10.1016/j.vaccine.2009.09.108