Structure-antioxidant relationships of sulfated galactomannan from guar gum.

Authors :: Wang X
Wang J
Zhang J
Zhao B
Yao J
Wang Y
Source :: International journal of biological macromolecules [Int J Biol Macromol] 2010 Jan 01; Vol. 46 (1), pp. 59-66. Date of Electronic Publication: 2009 Oct 28.
Publication Year :: 2010
Abstract: Sulfated polysaccharides exerted potential biological property which was relative to degree of sulfation (DS), M(w), substitution position and chain conformation. In the present study, commercial guar gum was purified and its sulfated derivates with different DS and M(w) were synthesized. FT-IR and 13C NMR analysis indicated that C-6 substitution was predominant in sulfated samples compared with other positions. In the sulfation reaction, a sharp decrease in M(w) was observed. The d(f) values from 1.92 to 2.85 indicated that the -SO3H groups led to the relatively expanded conformation of sulfated polysaccharides. Antioxidant assays showed that sulfated polysaccharides had better antioxidant activities. The data obtained in in vitro models indicated that high DS and low M(w) showed the best antioxidant capacities.<br /> (Crown Copyright 2009. Published by Elsevier B.V. All rights reserved.)