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The influence of the recipient's body weight on the probability to obtain a heart transplant-POLKARD HF registry.
- Source :
-
Transplantation proceedings [Transplant Proc] 2009 Oct; Vol. 41 (8), pp. 3166-70. - Publication Year :
- 2009
-
Abstract
- Introduction: The aim of the study was to analyze the influence of body weight of the adult heart recipient on the chance to obtain a transplant.<br />Methods: We analyzed the data from all 658 patients listed for heart transplantation.<br />Results: During the follow-up period, 325 (49%) of listed patients underwent transplantation with 102 (15%) succumbing before heart transplantation. The mean weight of transplanted patients was 73.7 +/- 13.7 kg and 81.2 +/- 15.4 kg for those not transplanted (P < .00001). Patients were divided according to body weight in two groups: light = below 80 kg (n = 360) or heavy > or = 80 kg or above (n = 297). On the transplant list, 111 heavy patients (37%) versus 213 light patients (59%) underwent the procedure, a significant difference. The waiting time among light patients was 255 versus heavy patients of 395 days (P < .005). There was a similar number of deaths before transplantation among the light (n = 56 360 patients; 15.5%) versus the heavy group (49/297; 16%). Upon multivariate Cox mode analysis independent factors related to not receiving a heart transplant were greater weight, systolic blood pressure, pulmonary vascular resistance, Heart Failure Survival Score (HFSS) score and lower N-terminal pro-brain natriuretic peptide (NTproBNP) levels.<br />Conclusions: Among adult heart transplant candidates, the chance to receive a heart transplant significantly decreased when the recipient's weight exceeded 80 kg. Patients with a body weight more than 110 kg had a poor chance to receive a heart transplantation.
- Subjects :
- Adult
Blood Pressure
Body Height
Diastole
Heart Failure mortality
Heart Failure surgery
Heart Rate
Heart Transplantation mortality
Heart Transplantation physiology
Humans
Middle Aged
Natriuretic Peptide, Brain blood
Overweight epidemiology
Peptide Fragments blood
Poland
Probability
Registries
Survival Rate
Survivors
Thinness epidemiology
Vascular Resistance
Ventricular Function, Left
Body Weight
Heart Failure physiopathology
Heart Transplantation statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2623
- Volume :
- 41
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 19857703
- Full Text :
- https://doi.org/10.1016/j.transproceed.2009.08.015